Hypertension and nephrotic syndrome induced by bevacizumab and fuquitinib:one case report
Hypertension and nephrotic syndrome induced by bevacizumab and fuquitinib in an elderly male was analyzed with a review of the relevant literature.After dosing of bevaci-zumab and fuquitinib,there was an onset of elevated blood pressure(190/110 mmHg),massive proteinuria(17.36 g·d-1),lower level of serum albumin(24.4g·L-1)and edema of both lower extremities.There was a high possibility of hyper-tension and secondary nephrotic syndrome due to bevacizumab and fuquitinib.The symptoms improved after a withdrawal of fuquinitinib,blood purification and symptomatic supports.
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