Effect of pharmacist-led chronic disease management on hypertensive patients under a medical consor-tium model
OBJECTIVE To evaluate the effect of pharmacist-led chronic disease management on hypertensive patients under a medical consortium model.METHODS From September 2022 to February 2023,this cohort study selected 307 hyper-tensive patients receiving medical care within the"1+2+3"pharmaceutical service medical consortium at Beijing TianTan Hospi-tal.They were randomized into two groups of intervention(n=148)and control(n=159).Intervention group received standard-ized medication therapy management services(MTMs)by pharmacists with follow-ups at Month 1/3/6 while control group tradi-tional pharmaceutical services only.The effect was evaluated from clinical,economic and humanistic outcomes.RESULTS After 6-month standardized MTMs intervention,systolic blood pressure decreased from(145.75±19.24)mmHg to(133.52±9.58)mmHg and diastolic blood pressure dropped from(94.01±11.29)mmHg to(86.31±7.73)mmHg.Blood pressure con-trol rate spiked from 36.49％to 68.24％,the incidence of adverse reactions dipped from 28.38％to 6.76％and medication adher-ence rate jumped from 33.11％to 66.22％.There were statistically significant differences(P＜0.01).A total of 308 drug-related problems were correlated with poor adherence(66.89％),need for additional medication therapy(23.65％)and adverse reactions(22.30％).After intervention,top three clinical outcomes included better control rates of blood pressure and comorbid-ity(72.30％),lowered instances of missed or forgotten doses(49.32％)and fewer or disappearing adverse reactions(28.38％).After intervention,daily medication expense per patient decreased by 1.38 yuan with a satisfaction rate of 100％.There were sig-nificant differences with control group(P＜0.01).CONCLUSION Under a medical consortium model,pharmacist-led chronic disease management may bring clinical and economic benefits and greater satisfaction to hypertensive patients.It is worthy of a wider promotion.
medical consortiumhypertension patientchronic disease managementpharmacist-ledmedication therapy man-agement servicesphysician-pharmacist collaboration
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