Participation of clinical pharmacists in nutritional assessments and interventions for patients with hepato-biliary and pancreatic malignancies
OBJECTIVE To explore the clinical applications of Nutritional Risk Screening 2002(NRS2002)and Patient-Generated Subjective Global Assessment(PG-SGA)in the screening and assessment of nutritional risk in patients with hepatobili-ary and pancreatic malignancies and explore the effects of nutritional therapy involving clinical pharmacists on rationality,effective-ness,length of stay and hospitalization expense.METHODS A total of 167 patients were divided into two groups of intervention(n=74)and control(n=93)according to whether or not clinical pharmacists participated in the formulation of nutritional treat-ment.Clinical pharmacists conducted nutritional assessments and individualized interventions of nutritional treatment for interven-tion group.The correlations were examined between nutritional risk,malnutrition,patient age,tumor site and consistency of screening evaluation tools.And two groups were compared in terms of rationality and effectiveness of treatment protocols,hospi-talization stay and hospitalization expense.RESULTS The incidence of nutritional risk in intervention and control groups was 55.4％and 49.5％respectively.And the incidence of malnutrition group was 81.1％in intervention.Statistical differences existed in the incidence of nutritional risk and PG-SGA classification among different ages and sites(P＜0.05).Statistically sig-nificant inter-group differences existed in energy supply,carbohydrate-lipid ratio,protein supply and parenteral nutrition infusion modes(P＜0.05).After pharmacists participated in nutritional treatment,albumin and prealbumin were significantly higher in intervention group than those in control group.And hospitalization expense was significantly lower in intervention group than that in control group(P＜0.05).The declining magnitudes of albumin and prealbumin were significantly lower in intervention group than those in control group(P＜0.05).CONCLUSION The incidence of moderate/severe malnutrition(PG-SGA grade C/D)is high in patients with hepatobiliary and pancreatic malignancies aged over 70 years.Nutritional therapy with an active participa-tion of clinical pharmacists can improve the rationality and effectiveness of treatment protocols,lower hospitalization expense,boost the level of nutritional therapy and optimize the outcomes of patients.
nutritional risk screening 2002patient-generated subjective global assessmentnutritional therapyclinical phar-macistpharmaceutical intervention
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