Advances of research and development on therapeutic targets and drugs for autism spectrum disorder
The pathogenesis of autism spectrum disorder(ASD)has remained elusive.Currently there are growing researches on the etiologies or therapeutic targets of ASD,such as stem cell therapy,microbiota-gut-brain axis,adeno-associated virus gene therapy,excitatory-inhibitory(E-I)imbalance,endocannabinoid(eCB)system and phosphoinositide3-kinase(PI3K)signaling pathway,etc.Some drugs have demonstrated some promising results.This reviews summarized the latest therapeutic targets and drug R & D for ASD.
autism spectrum disordertherapeutic targetsresearch and development of drugs