首页|国家组织集中采购质子泵抑制剂在全国范围医疗机构中的可及性调查研究

国家组织集中采购质子泵抑制剂在全国范围医疗机构中的可及性调查研究

扫码查看
目的:调研国家组织集中采购(以下简称"国家集采")质子泵抑制剂(PPIs)在全国范围内的可及性现状,为评价国家集采政策的实施效果提供参考依据.方法:以前5批国家集采药品中PPIs为调研对象,参照世界卫生组织/健康行动国际组织(WHO/HAI)标准调查法,分别从可获得率、限定日费用(DDDc)、用药频度(DDDs)和可负担性4个维度对我国31个省级行政区900余家二、三级公立综合医院进行调查.结果:国家集采政策实施后,PPIs的可获得性明显提高和呈现逐批次递增趋势,同时PPIs在三级医院的可获得性均显著高于二级医院,越发达的地区可获得性越高;PPIs的DDDs显著提高(增长6 634.40%),其中泮托拉唑钠肠溶片和艾司奥美拉唑镁肠溶片的DDDs和增幅均排在前列;PPIs的DDDc大幅降低(平均降幅83.73%),大部分PPIs的DDDs随着DDDc的降低而升高;对于农村和城镇居民,PPIs的可负担性均明显提升,并且我国居民对绝大多数PPIs有较好的可负担性.结论:国家集采政策实施后PPIs的可获得性和DDDs均显著提高,DDDc显著下降,可负担性明显提升,国家集采政策提高了 PPIs的可及性,公立综合医院执行国家集采政策效果显著.
Accessibility of national-organized centralized procurement of proton pump inhibitors at medical institu-tions nationwide
OBJECTIVE To explore the accessibility of national-organized centralized procurement of proton pump inhibitors(PPIs)nationwide to provide references for evaluating the implementation outcome of national centralized procurement policy.METHODS The previous five batches of nationally procured PPIs were utilized as research objects.According to the standard survey scheme of World Health Organization/Health Action International(WHO/HAI),over 900 secondary/tertiary public gen-eral hospitals in 31 provincial-level administrative regions of China were surveyed from four dimensions of availability rate,defined daily dose cost(DDDc),defined daily doses(DDDs)and affordability.RESULTS After an implementation of national central-ized procurement policy,availability of PPIs significantly improved with a rising trend of batch by batch.At the same time,avail-ability of PPIs at tertiary hospitals was significantly higher than that at secondary hospitals and availability was higher in more developed areas;DDDs of PPIs jumped sharply by 6 634.40%).And DDDs and spikes of pantoprazole sodium enteric-coated tablets and esomeprazole magnesium enteric-coated tablets ranked at the forefront;DDDc of PPIs dropped by an average decline of 83.73%while DDDs of most PPIs rose;for both rural and urban residents,affordability of PPIs has improved obviously and Chinese residents enjoyed better affordability for most PPIs.CONCLUSION After an implementation of national centralized pro-curement policy,both availability and DDDs of PPIs have significantly improved while DDDc has significantly lowered with a greater affordability.National centralized procurement policy has greatly improved the accessibility of PPIs.Public general hospi-tals have achieved remarkable outcomes in implementing the national centralized procurement policy.

national-organized centralized procurement of drugsproton pump inhibitorsaccessibilitydefined daily dose costdefined daily doses

王梦雷、陆伟、陈红斗、李伟、赵园园、叶露、杨晴晴、吴欢欢

展开 >

徐州医科大学附属宿迁医院/南京鼓楼医院集团宿迁医院药学部,江苏宿迁 223800

徐州医科大学江苏省新药研究与临床药学重点实验室,江苏徐州 221004

国家组织集中采购药品 质子泵抑制剂 可及性 限定日费用 用药频度

江苏省新药研究与临床药学重点实验室资助项目江苏省药学会-奥赛康医院药学基金科研项目

KFKT-2105A202148

2024

中国医院药学杂志
中国药学会

中国医院药学杂志

CSTPCD北大核心
影响因子:1.198
ISSN:1001-5213
年,卷(期):2024.44(19)