Drug-interaction between antiepileptic drugs and herb remedies,dietary supplements,healthy products and food:based upon literature reports
OBJECTIVE To provide a systematic presentation about drug-interaction between antiepileptic drug and herb remedies,dietary supplements,healthy products,food,help medical professional to further management pharmaceutical risk.METHODS The databases of PubMed,China National Knowledge Infrastructure(CNKI),Wanfang and CQVIP were searched for the eligible literature items.And drug database of National Medical Products Administration(NMPA),special food information query platform of State Administration for Market Regulation(SAMR),Chinese Pharmacopoeia,local Chinese medi-cine decoction preparation standards,JD.com and Taobao were accessed for confirming the existence of common names included in herb remedies,dietary supplements,healthy products and foods in China.RESULTS A total of 48 herb remedies,dietary supplements,healthy products and food-antiepileptic drug interaction pairs were identified from published literature,14 pairs from case report and 30 pairs from in vivo/vitro study.CONCLUSION Researches on the interaction between herb remedies,dietary supplements,healthy products,food and anti-epileptic drugs have remained insufficient.Although this study provides a system-atic summary of information on such interactions for healthcare professionals,further establishment of databases and development of effective tools are required for a proper management of medication risks in clinical practices.
NETL
NSTL
万方数据
