OBJECTIVE:To probe into the efficacy of Cai's endometriosis Ⅲ formula in the treatment of endometriosis syndrome of damp-heat and blood stasis.METHODS:Forty patients with endometriosis syndrome of damp-heat and blood stasis admitted into Shuguang Hospital of Shanghai University of Traditional Chinese Medicine from Jul.2021 to Dec.2022 were extracted and treated with Cai's endometriosis Ⅲ formula for 2 courses of treatment(6 menstrual cycles).Visual analogue scale(VAS),traditional Chinese medicine syndrome score,pelvic mass volume and serum CA125 level were compared before and after 2 courses of treatment.RESULTS:Before treatment,the VAS score of the patient was(6.16±1.44)points and traditional Chinese medicine syndrome score was(23.78± 7.80)points.After treatment,the VAS score of the patients was(5.18±1.58)points,and traditional Chinese medicine syndrome score was(20.15±5.94)points,both of which decreased compared to before treatment,with statistically significant differences(P<0.05).After treatment,the CA125 level of the patients was lower than that before treatment,and the cysts of B-ultrasound were lower than that before treatment,with statistically significant difference(Z=-2.401,-2.514,P<0.05).CONCLUSIONS:Cai's endometriosis Ⅲ formula can reduce patients'VAS score,alleviate pain symptoms,improve traditional Chinese medicine symptom,decrease blood CA125,and inhibit the growth of ovarian endometriosis cysts.
关键词
子宫内膜异位症/蔡氏内异Ⅲ方/湿热瘀结/痛经/血清糖类抗原125
Key words
Endometriosis/Cai's endometriosis Ⅲ formula/Damp-heat and blood stasis/Dysmenorrhea/CA125