Clinical Application of Chinese Patent Medicines in a Grade Ⅲ,Level A Integrated Traditional Chinese and Western Medicine Hospital from 2021 to 2022
OBJECTIVE:To probe into the clinical application rationality of Chinese patent medicines based on the application of Chinese patent medicine and the review of special medical orders in a grade Ⅲ,level A integrated traditional Chinese and Western Medicine hospital(hereinafter referred to as"the hospital").METHODS:Retrospective study was conducted to analyze the categories,consumption sum,use intensity,defined daily dose system(DDDs),drug consumption sum ranking(B)/DDDs ranking(A)and adverse drug reactions(ADR)related to Chinese patent medicines in the ward of the hospital from 2021 to 2022.Totally 4 800 inpatient medical orders with Chinese patent medicines from 2021 to 2022 were selected for special medical order review,and irrational drug use problems existing in clinical application of Chinese patent medicines were summarized and analyzed.RESULTS:Traditional Chinese medicine injections were widely used in the inpatient department of this hospital.The top 5 drugs ranked by consumption sum in 2 consecutive years included Shenkang injection,brucea jananica oil injection,and Xingnaojing injection.Shenkang injection and brucea jananica oil injection ranked the top 3 in terms of use intensity.The drugs with B/A＞1.5 were Ningmitai capsules,Kuanxiong aerosol inhalation and Peiyuan Tongnao capsules,Shenkang injection with B/A＜0.5 for 2 consecutive years,while the B/A of most Chinese patent medicines was from 0.5 to 1.5.Among the 4 800 inpatient medical orders with Chinese patent medicines,there were 465 cases(9.69％)with irrational drug use.The irrational drug use problems were mainly related to drugs of dampness removing,drugs of blood stasis removing and resuscitation,which were mainly manifested as inappropriate indications,repeated drug use,improper drug combination,and inappropriate usage,dosage and course of treatment.In the ADR reports related to Chinese patent medicines,oral dosage forms accounted for the highest proportion,followed by injections.CONCLUSIONS:The clinical application of Chinese patent medicine in the hospital is basically reasonable,and it is necessary to focus on the use of traditional Chinese medicine injections and ADR,and further promote clinical rational drug use and reduce adverse drug reactions by carrying out the relevant work of medical order review and strengthening medication supervision.
Chinese patent medicinesClinical applicationTraditional Chinese medicine injectionsMedical order reviewRational drug use
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