OBJECTIVE:To evaluate the economical efficiency of Luobufukebiri pills in the treatment of asthenospermia.METHODS:The cost-effectiveness of Luobufukebiri pills in the treatment of asthenospermia was analyzed based on the published randomized controlled trials of Luobufukebiri pills for the treatment of asthenospermia.RESULTS:After patient administration,the therapeutic regimen of Luobufukebiri pills was higher than the therapeutic regimen of Vitamin E soft capsules in terms of improving the percentage of forward sperm motility and total effective rate.Taking Vitamin E soft capsule as a reference,for the difference value in the percentage of forward sperm motility before and after,the incremental cost-effectiveness ratio(ICER)of Luobufukebiri pills was calculated to be 11 452.30,and the additional cost to reach the clinical significance cut-off value was 3 664.74 yuan,which is about 10.43%of China's per capita disposable income(PCDI,35 128.00 yuan)in 2021;for the total effective rate after treatment,the ICER of Luobufukebiri pills was calculated to be 4 094.10,which is about 11.65%of PCDI in China in 2021.CONCLUSIONS:Based on the assumption of China's PCDI in 2021 as the threshold of patients'willingness to pay,the application of Luobufukebiri pills has more economical efficiency than that of the Vitamin E soft capsules in improving the difference value in the percentage of forward sperm motility and promoting the clinical total effective rate.Carrying out the economic evaluation of Luobufukebiri pills in the treatment of asthenospermia contributes to improving the overall efficiency of medical resource allocation.
关键词
药物经济学/罗补甫克比日丸/维生素E软胶囊/弱精子症
Key words
Pharmacoeconomics/Luobufukebiri pills/Vitamin E soft capsules/Asthenospermia
维普
万方数据