OBJECTIVE:To perform comprehensive evaluation on Gushukang capsules,so as to provide reference for the clinical rational application of Gushukang capsules.METHODS:Knowledge system of evidence-based medicine,epidemiology and medical statistics was used,in combination with the relevant literature,data and information provided by drug manufacturers,to conducted a comprehensive evaluation study on efficacy,safety,economical efficiency,pharmacological characteristics and quality of Gushukang capsules.RESULTS:Meta-analysis on efficacy of Gushukang capsules showed that its clinical effect was better than single calcium agent,which can effectively target primary osteoporosis with a low incidence of adverse drug reactions;with quick absorption,high bioavailability and convenient administration.And the quality of the drug met the national standard and was controllable,its dispensatory,labeling and packaging complied with the current regulations.The price of the drug was reasonable and had been included in the national reimbursement drug list,with a certain degree of economical efficiency.CONCLUSIONS:Gushukang capsules have high safety,controllable quality,significant clinical efficacy,convenient administration and reasonable economical efficiency.However,the evidence level of part of studies is relatively low,and relatively few studies have been conducted on its in vivo pharmacological properties and accessibility,and further in-depth exploration is recommended.
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