Cooperation Among Multi-Center Drug Clinical Trial Institutions in Pediatric Population in China
OBJECTIVE:To research the development of clinical trials in the pediatric population in China,analyze the trend and characteristics of cooperation among clinical trial institutions,so as to provide reference for constructing pediatric clinical medical research system.METHODS:Based on clinical trial research data of pediatric population published on the platform for registry and publicity of drug clinical trials by the Center for Drug Evaluation of National Medical Products Administration from 2013 to 2022,characteristics and cooperation trends were analyzed by using quantitative analysis and social network analysis methods.RESULTS:Among the 640 publicized projects,multi-center clinical research of drugs accounted for 87.50%(560 projects).Anti-tumor drugs and immunomodulators,blood and hematopoietic system drugs were popular categories in children's drug research and development.Core institutions and core principal investigator with high-quality clinical trial resources were relatively concentrated.CONCLUSIONS:Clinical trial research of drugs in the pediatric population in China are increasing,with frequent cooperation among some institutions and a loose cooperation network density,which requires further strengthening of cooperation.
Pediatric populationMulti-center clinical trial of drugsSocial network analysis
万方数据
维普
