Bibliometric and Visual Analysis of Vancomycin Use in Patients with Renal Replacement Therapy
OBJECTIVE:To explore the current status and trends on vancomycin use in patients with renal replacement therapy.METHODS:Based on the Web of Science Core Collection,literature related to vancomycin use in patients with renal replacement therapy published from Jan.1st,2007 to Oct.11th,2023 was searched.Bibliometric and visualization analysis were performed by using VOSviewer and CiteSpace software,including publication trends,geographic distribution characteristics,authors and institutions,journal distribution characteristics,and keyword information.RESULTS:A total of 747 publications were included.Since 2007,the number of publications in related fields had fluctuated and increased,with the United States(264 publications)being the country with the most publications,followed by Australia(76 publications)and China(71 publications).The University of Queensland(49 publications)had the most publications.Jason A Roberts(24 publications),David W Johnson(19 publications)and Jeffrey Lipman(19 publications)were the top 3 authors with the highest number of publications.Peritoneal Dialysis International(47 publications)was the the journal that had published the most relevant literature.Keywords in recent years had focused on topics such as acute renal injury,dosing regimens,therapeutic drug monitoring,population pharmacokinetics,and continuous renal replacement therapy.CONCLUSIONS:The optimal dose of vancomycin in patients on renal replacement therapy is unknown.It is a hot topic and trend in the field to give patients the appropriate dosing regimen through therapeutic drug monitoring and population pharmacokinetic modeling to achieve anti-infective efficacy and avoid adverse drug reactions.There is a lack of close cooperation and communication between Chinese research organizations and the international community.
Renal replacement therapyVancomycinBibliometricsDosing regimensTherapeutic drug monitoring
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