Effects of Traditional Chinese Medicine External Washing Protocol on Process of Wound Healing in Patients After Perianal Abscess Surgery
OBJECTIVE:To probe into the effects of traditional Chinese medicine external washing protocol on process of wound healing in patients after perianal abscess surgery.METHODS:Totally 100 patients with perianal abscess surgery in the hospital from Mar.2019 to Mar.2023 were extracted to be divided into the observation group and control group via the random number table method,with 50 cases in each group.The control group was treated with potassium permanganate sitz bath,while the observation group received traditional Chinese medicine external washing protocol,both groups were treated for 2 weeks.Traditional Chinese medicine syndrome scores,clinical efficacy,wound rehabilitation(degree of anal pain,wound bleeding and wound healing),wound healing time(time for rotting flesh shedding,time for wound epithelium emergence,time for wound healing),inflammatory factors[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),IL-8],transforming growth factor-β1(TGF-β1)and vascular endothelial growth factor(VEGF)levels before and after intervention were analyzed.RESULTS:After intervention,the scores of perianal swelling,dry mouth and constipation,chilliness and fever,restlessness and difficulty in urination in two groups were lower than those before intervention,and the observation group was lower than the control group,with statistically significant differences(P<0.05).The total effective rate of observation group(47/50,94.00%)was higher than that of control group(40/50,80.00%),the difference was statistically significant(P<0.05).After intervention,the scores of anal pain,wound bleeding and wound healing in two groups were lower than those before intervention,and the observation group was lower than the control group,with statistically significant differences(P<0.05).The time of rotting flesh shedding,wound epithelium emergence and wound healing in the observation group were shorter than those in the control group,with statistically significant differences;after intervention,serum levels of IL-6,TNF-α and IL-8 in two groups were lower than those before intervention,and the observation group was lower than the control group;after intervention,the serum levels of TGF-β1 and VEGF in two groups were higher than those before intervention,and the observation group was higher than the control group,with statistically significant differences(P<0.05).CONCLUSIONS:Application of traditional Chinese medicine external washing protocol in patients after perianal abscess surgery can effectively alleviate the clinical symptoms of patients,improve wound healing,reduce the levels of inflammatory factors,and up-regulate the levels of TGF-β1 and VEGF,which is conducive to improving the overall intervention effect.
Perianal abscessTraditional Chinese medicine external washing protocolInflammatory factorsTransforming growth factor-β1Vascular endothelial growth factor
万方数据
维普
