Clinical Study on Baiyi Rectal Solution Combined with Danbai Granules in the Treatment of Sequelae of Pelvic Inflammatory Disease(Damp-Heat Stasis Type)
OBJECTIVE:To probe into the clinical efficacy of Baiyi rectal solution combined with Danbai granules in the treatment of sequelae of pelvic inflammatory disease(damp-heat stasis type).METHODS:Totally 90 patients with sequelae of pelvic inflammatory disease(damp-heat stasis type)admitted into the hospital from Mar.2021 to Mar.2023 were extracted to be divided into the traditional Chinese medicine enema group,traditional Chinese medicine granule group and combined group via the random number table method,with 30 cases in each group.The traditional Chinese medicine enema group was treated with conventional treatment+Baiyi rectal solution,the traditional Chinese medicine granule group was given conventional treatment+Danbai granules,and the combined group received conventional treatment+Baiyi rectal solution+Danbai granules.After 3 menstrual cycles of treatment,the clinical efficacy,traditional Chinese medicine syndrome score,hemodynamics,inflammatory factors and treatment safety of three groups were evaluated.RESULTS:The total effective rate of combined group was 93.33%(28/30),higher than 70.00%(21/30)of traditional Chinese medicine enema group and 66.67%(20/30)of traditional Chinese medicine granule group,with statistically significant differences(P<0.05).After treatment,the scores of traditional Chinese medicine symptom(including lumbosacral swelling pain,poor menses,increased underband,red tongue and yellow fur)in combined group were lower than those in traditional Chinese medicine enema group and traditional Chinese medicine granule group,with statistically significant differences(P<0.05).After treatment,the systolic maximum flow velocity,end-diastolic maximum flow velocity and pulsation index of uterine artery in combined group were higher than those in traditional Chinese medicine enema group and traditional Chinese medicine granule group,and the resistance index was lower than those in traditional Chinese medicine enema group and traditional Chinese medicine granule group,with statistically significant differences(P<0.05).After treatment,the levels of inflammatory factors(interleukin-18,prostaglandin E2 and β amyloid precursor protein)in combined group were lower than those in traditional Chinese medicine enema group and traditional Chinese medicine granule group,with statistically significant differences(P<0.05).The incidences of adverse drug reactions in combined group,traditional Chinese medicine enema group and traditional Chinese medicine granule group were respectively 13.33%(4/30),10.00%(3/30)and 6.67%(2/30),with no statistically significant difference(P>0.05).CONCLUSIONS:The efficacy of Baiyi rectal solution combined with Danbai granules in the treatment of sequelae of pelvic inflammatory disease(damp-heat stasis type)is significant,which can improve the traditional Chinese medicine symptom of patients,increase the hemodynamics of patients'pelvic uterine artery,inhibit the level of inflammatory factors with higher safety.
万方数据
维普
