Influencing Factors of Potentially Inappropriate Medication in the Elderly with Osteoporosis
OBJECTIVE:To probe into the influencing factors of potentially inappropriate medication(PIM)in the elderly with osteoporosis.METHODS:Data of elderly inpatients with osteoporosis in Guangyuan Central Hospital from Jan.to Jun.2022 were collected.Beers criteria of American Geriatrics Society(2023 Edition)were used to analyze PIM of patients,and multivariate Logistic regression was used to analyze the influencing factors of PIM.RESULTS:PIM was present in 449 cases(71.61%)of 627 patients included,of which 367 cases(58.53%)were drug-related,143 cases(22.81%)were associated with disease or symptoms,211 cases(33.65%)were associated with caution of drug use,33 cases(5.26%)were associated with drug interactions,and 29 cases(4.63%)were associated with renal function.Logistic regression analysis showed that compared with patients with length of stay<10 d,clinical diagnosis≤7 kinds of diseases,number of drug varieties≤15,non-surgery and no antibiotics,the risk of PIM was higher in patients with length of stay≥15 d,clinical diagnosis≥14 kinds of diseases,number of drug varieties≥31,surgery and antibiotics,with statistically significant differences(P<0.05).CONCLUSIONS:Elderly osteoporosis patients with multiple diseases have a higher incidence of PIM.The main influencing factors for PIM are length of stay≥15 d,clinical diagnosis≥14 kinds of diseases,number of drug varieties≥31,surgery during hospitalization and use of antibiotics.
Elderly patients with osteoporosisPotentially inappropriate medicationInfluential factors
万方数据
维普
