Effect Analysis of Multi-Department Joint Intervention of Perioperative Prophylactic Application of Antibiotics for Gastric Cancer
OBJECTIVE:To explore the effect of multi-department joint intervention of perioperative prophylactic application of antibiotics for gastric cancer,so as to provide reference for the rational application of antibiotics in the perioperative period.METHODS:The hospital adopted multi-department joint intervention in the perioperative prophylactic application of antibiotics for gastric cancer.The prophylactic application of antibiotics in perioperative period and the clinical indicators of 104 cases with gastric cancer before intervention(from Jan.2020 to Sept.2021)and 94 cases with gastric cancer after intervention(from Oct.2021 to Sept.2022)were compared.RESULTS:Compared with before intervention,the rational rate of prophylactic application of antibiotics in perioperative period for gastric cancer patients after intervention increased from 25.0%(26/104)to 93.6%(88/94),and the rate of drug combination decreased from 73.1%(76/104)to 1.1%(1/94);the total duration of medication decreased from 4.0(3.0,5.0)d to 3.0(3.0,3.0)d,and the proportion of patients with total duration>48 to 72 h increased from 42.3%(44/104)to 81.9%(77/94),the proportion of patients with total duration of medication>72 h decreased from 55.8%(58/104)to 13.8%(13/94);the use intensity of antibiotics decreased from 21.3(16.8,31.7)DDDs/(100 people·d)to 14.5(12.6,18.7)DDDs/(100 people·d);the total cost per capita for prophylactic application of antibiotics decreased from 184.5(126.7,887.4)yuan to 134.6(95.4,168.3)yuan,the differences were statistically significant(P<0.05).There was no significant difference in postoperative surgical site infection rate,other infection rate and postoperative length of stay before and after intervention(P>0.05).The number of successful cases of intervention by pharmacists was 42,the qualified rate of training assessment in clinicians was 100%,and the examination of antibiotics in the department met the requirements.CONCLUSIONS:The rationality of perioperative prophylactic application of antibiotics in gastric cancer can be effectively improved through multi-department joint intervention,which do not adversely affect the clinical indicators.
万方数据
维普
