中药干预人肺腺癌A549细胞的实验研究进展
Progress of Experimental Research on Intervention of Traditional Chinese Medicine in Human Lung Adenocarcinoma A549 Cells
周佳静 1张利 2侯爱画 1崔长磊 1严吉峰3
作者信息
- 1. 烟台市中医医院肿瘤科,山东 烟台 264000
- 2. 山东中医药大学第一临床医学院,济南 250011
- 3. 山东省烟台护士学校临床教学部,山东 烟台 264000
- 折叠
摘要
恶性肿瘤中,肺癌在国内和世界范围内的发病率、死亡率均居首位.非小细胞肺癌是主要的肺癌类型,而肺腺癌是非小细胞肺癌中常见的病理类型.A549 细胞是一种实验用肺癌细胞,常被用于肺腺癌的研究模型.由于中药的低毒、有效、安全等特点,越来越多的研究聚焦于中药治疗肺癌的作用机制.目前,关于中药对肺腺癌A549 细胞的实验研究不断开展,笔者经过查阅大量相关文献,将研究分为中药复方和中药单体的干预研究,对其进行综述.
Abstract
Among malignant tumors,lung cancer has the highest morbidity and mortality both domestically and worldwide.Non-small cell lung cancer is the main type of lung cancer,while lung adenocarcinoma is a common pathologic type of non-small cell lung cancer.A549 cells are a type of experimental lung cancer cells commonly used as research models for lung adenocarcinoma.Due to the characteristics of low toxicity,significant efficacy and high safety of traditional Chinese medicine,more and more studies focus on the mechanism of traditional Chinese medicine in the treatment of lung cancer.At present,experimental studies on the effects of traditional Chinese medicine on lung adenocarcinoma A549 cells have been continuously carried out.After reviewing a large amount of relevant literature,the studies are categorized into intervention studies of traditional Chinese medicine compounds and traditional Chinese medicine monomers,which were reviewed.The following is a summary of these studies.
关键词
肺腺癌/A549细胞/中药/实验研究Key words
Lung adenocarcinoma/A549 cells/Traditional Chinese medicine/Experimental research引用本文复制引用
基金项目
山东省自然科学基金青年项目(ZR2021QH023)
山东省医务职工科技创新计划项目(SDYWZGKCJHLH202277)
出版年
2024
国家科技期刊平台
NSTL
万方数据