The Application of GRADE System in Clinical Guideline Development Regarding Hospital Pharmacy
There are many systems of rating quality of evidence and grading strength of recommendations,this may cause confusion for clinicians when reading guideline evidence and recommendations.Grading of Recom-mendations Assessment,Development,and Evaluation(GRADE)system is the most widely used rating system in the world.This article is to briefly introduce the evidence rating and 4 main factors of formulating recommendations in GRADE.We will use several published guidelines led by Chinese hospital pharmacy as examples to illustrate GRADE system,to help clinicians understand GRADE system and apply guideline evidence and recommendations into clinical practice with critical thinking.