医院药学指南制定中的证据与推荐意见GRADE系统评级方法及应用
The Application of GRADE System in Clinical Guideline Development Regarding Hospital Pharmacy
叶志康 1翟所迪2
作者信息
- 1. 麦克马斯特大学Michael G.DeGroote国家疼痛中心,加拿大 安大略省 汉密尔顿L8S4L8
- 2. 北京大学医学部药物评价中心,北京 100191;北京大学第三医院药剂科,北京 100191
- 折叠
摘要
目前,国际上存在多种证据与推荐意见分级系统,对临床医务工作者阅读指南证据和推荐意见造成困扰.证据推荐分级的评估、制定与评价(GRADE)系统目前是全球使用最为广泛的证据与推荐意见分级系统,本文简单地介绍GRADE系统证据质量评级及影响推荐意见形成的 4 个主要因素,并结合中国医院药学界发起制定的、在国际上发表的几部药学指南举例阐述,以帮助临床医务工作者了解GRADE系统,以批判性思维运用指南证据和推荐意见指导临床实践行为.
Abstract
There are many systems of rating quality of evidence and grading strength of recommendations,this may cause confusion for clinicians when reading guideline evidence and recommendations.Grading of Recom-mendations Assessment,Development,and Evaluation(GRADE)system is the most widely used rating system in the world.This article is to briefly introduce the evidence rating and 4 main factors of formulating recommendations in GRADE.We will use several published guidelines led by Chinese hospital pharmacy as examples to illustrate GRADE system,to help clinicians understand GRADE system and apply guideline evidence and recommendations into clinical practice with critical thinking.
关键词
临床指南/证据/推荐意见/GRADEKey words
Clinical guideline/Evidence/Recommendations/GRADE引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据