Establishment and Application of Drug Utilization Evaluation Criteria for Aminomethylbenzoic Acid Injection
OBJECTIVE:To establish the drug utilization evaluation(DUE)criteria of aminomethylbenzoic acid injection,so as to provide reference for rational clinical application of aminomethylbenzoic acid injection.METHODS:By constructing the basic content of DUE criteria,based on the drug instructions of aminomethylbenzoic acid injection,referring to relevant guidelines and literature and expert consultation method,the DUE criteria of aminomethylbenzoic acid injection was established.Retrospective study was performed to evaluate the application rationality of aminomethylbenzoic acid injection in a tertiary hospital in Hunan Province from Jan.to Jun.2022,including indications,usage and dosage,drug combination,contraindications,adverse drug reactions monitoring.RESULTS:The established DUE criteria for aminomethylbenzoic acid injection were categorized into three levels,including 3 primary indicators,9 secondary indicators,and 28 tertiary indicators.A total of 500 patients using aminomethylbenzoic acid injection were included,169 cases fully met the DUE criteria,with a rational rate of 33.80%;331 cases did not fully meet the criteria,with an irrational rate of 66.20%,irrational medication was commonly found in inappropriate indications(233 cases,70.39%)and improper usage and dosage(222 cases,67.07%).CONCLUSIONS:The DUE criteria for aminomethylbenzoic acid injection established in this study are highly scientific,practical and feasible,and the evaluation process is easy to operate and the results are comprehensive and intuitive,which can be used to standardize the rational application of aminomethylbenzoic acid injection in clinical practice.
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