OBJECTIVE:To explore the quality of clinical practice guidelines related to application of aspirin in preventing preeclampsia during pregnancy at home and abroad.METHODS:Clinical practice guidelines related to application of aspirin in preventing preeclampsia during pregnancy published from 2012 to 2023 were systematically retrieved,the Appraisal of Guidelines for Research and Evaluation Ⅱ(AGREE Ⅱ)were used to perform evaluation and analysis on the quality of enrolled guidelines,and to conduct comparison and summary on the main recommendations in each guidelines.RESULTS:A total of 18 clinical practice guidelines related to application of aspirin in preventing preeclampsia during pregnancy were enrolled,4 of which were A-level recommendation,13 were B-level recommendation and 1 was C-level recommendation.Results of general guideline evaluation based on AGREE Ⅱ indicated that the average scores were respectively 62.96％,60.03％,62.21％,96.14％,43.06％,66.20％in the fields of range and purpose,participants,preciseness,explicitness,applicability,independence.Currently,the preventive application of aspirin for pregnant women with certain risk of preeclampsia were recommended in guidelines of various countries,while there were differences in the recommended treatment course and dosage of aspirin.CONCLUSIONS:Among the guidelines on aspirin for the prevention of preeclampsia published globally in the last 10 years,there are a relatively large number of moderate-quality and high-quality guidelines,with the main shortcomings centered in the applicability filed,as well as in items such as target population perspectives,selection criteria of evidence and involvement of external reviewers,which require further improvement by guideline developers.
关键词
阿司匹林/子痫前期/预防/指南研究和评估工具Ⅱ/指南评价
Key words
Aspirin/Preeclampsia/Prevention/the Appraisal of Guidelines for Research and Evaluation Ⅱ/Guideline evaluation
维普
万方数据