Effects of Qibei Capsule Combined with Linezolid on Traditional Chinese Medicine Syndrome and Lesion Absorption in Patients with Multidrug-Resistant Pulmonary Tuberculosis of Qi and Yin Deficiency Type
OBJECTIVE:To probe into the effects of Qibei capsule combined with linezolid on traditional Chinese medicine syndrome and lesion absorption in patients with multidrug-resistant pulmonary tuberculosis of Qi and Yin deficiency type.METHODS:Totally 120 patients with multidrug-resistant pulmonary tuberculosis of Qi and Yin deficiency type admitted into the hospital from Feb.2020 to Feb.2022 were extracted to be divided into the linezolid group and Qibei capsule group via the random number table method,with 60 cases in each group.The linezolid group was given standard anti-tuberculosis regimen+linezolid treatment,while the Qibei capsule group received Qibei capsule on the basis of the linezolid group.The traditional Chinese medicine syndrome scores and lesion absorption of both groups were compared.RESULTS:After treatment,the traditional Chinese medicine syndrome scores such as cough,night sweats,and hot flashes in the Qibei capsule group were lower than those in the linezolid group,and the lesion absorption rate and sputum bacterial negative conversion rate were higher than those in the linezolid group,with statistically significant differences(P＜0.05).Compared with before treatment,the levels of CD4+and CD4+/CD8+in both groups increased,and the Qibei capsule group was higher than the linezolid group;the level of CD8+in both groups decreased,and the Qibei capsule group was lower than the linezolid group,with statistically significant differences(P＜0.05).CONCLUSIONS:Qibei capsule combined with linezolid in the treatment of patients with multidrug-resistant pulmonary tuberculosis of Qi and Yin deficiency type can effectively decrease the traditional Chinese medicine syndrome scores in patients,promote the lesions absorption and sputum bacterial negative conversion rate,and improve immune function.
Qibei capsuleLinezolidMultidrug-resistant pulmonary tuberculosisQi and Yin deficiency typeTraditional Chinese medicine syndromeLesion absorption
万方数据
维普
