目的:对"冬病夏治法"用于慢性阻塞性肺疾病(COPD)的临床疗效进行系统评价，以期为COPD的防治及冬病夏治的临床应用提供有价值的循证依据。方法:检索中国知网、万方数据库、维普数据库、PubMed、Web of Science、Embase(检索时间为建库至2023年8月)，筛选较高质量的冬病夏治法用于COPD的临床随机对照试验研究(对照组采用常规疗法，如给予支气管舒张剂、吸入糖皮质激素、氧疗、戒烟等;研究组在对照组的基础上加用"冬病夏治法"或者单纯采用"冬病夏治法")，提取数据，应用RevMan 5。4。1软件进行Meta分析。结果:最终纳入65项随机对照试验研究，涉及5 736例受试者(研究组2 880例，对照组2 856例)。Meta分析结果表明，与常规疗法比较，"冬病夏治法"用于COPD的治疗可提高总有效率(OR=3。97，95％CI=3。32～4。74，P＜0。000 01)，提高第1秒用力呼气容积占用力肺活量百分比(MD=3。76，95％CI=2。66～4。85，P＜0。000 01)，降低圣乔治呼吸问卷评分(MD=-4。83，95％CI=-6。39～-3。27，P＜0。000 01)，差异均有统计学意义。结论:现有证据表明，对于COPD患者，在常规疗法的基础上加用中医"冬病夏治法"或单纯采用"冬病夏治法"，治疗效果更好。
Systematic Review on Effects of"Treatment of Winter Diseases in Summer"for Chronic Obstructive Pulmonary Disease
OBJECTIVE:To systematically review the clinical efficacy of"treatment of winter diseases in summer"for chronic obstructive pulmonary disease(COPD),so as to provide valuable evidence-based basis for the prevention and treatment of COPD and clinical application of"treatment of winter diseases in summer".METHODS:CNKI,Wanfang Data,VIP,PubMed,Web of Science,and Embase databases were retrieved(the retrieval time was from the establishment of the database to Aug.2023)to collect the high-quality clinical randomized controlled trial of"treatment of winter diseases in summer"for COPD(the control group received conventional therapy,such as bronchodilator,inhaled glucocorticoid,oxygen therapy,and smoking cessation;the study group received"treatment of winter diseases in summer"on the basis of the control group or simply received"treatment of winter diseases in summer").Data were extracted and Meta-analysis was performed by using RevMan 5.4.1 software.RESULTS:Totally 65 randomized controlled trials were enrolled,including 5 736 patients(with 2 880 cases in study group and 2 856 cases in control group).Meta-analysis showed that compared with conventional therapy,"treatment of winter diseases in summer"could improve the total effective rate of COPD(OR=3.97,95％CI=3.32-4.74,P＜0.000 01),increase the percentage of forced expiratory volume in one second to forced vital capacity(MD=3.76,95％CI=2.66-4.85,P＜0.000 01),decrease the score of St George's respiratory questionnaire(MD=-4.83,95％CI=-6.39--3.27,P＜0.000 01),the differences were statistically significant.CONCLUSIONS:Existing evidence suggests that for COPD patients,the treatment effect is better if the traditional Chinese medicine"treating winter disease in summer"or"treating winter disease in summer"is added on the basis of conventional therapy.
"Treatment of winter diseases in summer"Chronic obstructive pulmonary diseaseAcupoint applicationMeta-analysisSystematical review
万方数据
