Effects of Clinical Pharmacists'Intervention on Rational Application of Edaravone and Dexborneol Concentrated Solution for Injection in Patients with Stroke
Effects of Clinical Pharmacists'Intervention on Rational Application of Edaravone and Dexborneol Concentrated Solution for Injection in Patients with Stroke
OBJECTIVE:To probe into the role of clinical pharmacists'intervention in improving the application rationality of edaravone and dexborneol concentrated solution for injection in patients with stroke and its effects on diagnosis-related groups(DRG)payment.METHODS:Related information of patients with stroke who received treatment and were given edaravone and dexborneol concentrated solution for injection in Guangyuan Central Hospital from Sept.2022 to Jun.2023 were retrospectively analyzed,147 patients before intervention(from Sept.1st,2022 to Feb.24th,2023)and 149 patients after intervention(from Feb.25th to Jun.30th,2023)by clinical pharmacists were enrolled to compare the incidences of irrational medical orders and adverse drug reactions before and after the intervention,as well as the average length of stay,drug costs,hospitalization costs and profit/loss after DRG payment.RESULTS:After intervention,the incidence of irrational medical orders was 19.46%(29/149),lower than that before intervention(80.95%,119/147).After intervention,1 patient had adverse drug reactions,less than 5 patients before intervention.After intervention,the average length of stay was 10.56 d,shorter than 12.60 d of before intervention.The average drug cost,average hospitalization cost and profit/loss after DRG payment were 7 300.07 RMB,28 592.75 RMB and 3 347.83 RMB loss,respectively,which were lower than 9 437.71 RMB,34 740.39 RMB and 4 408.02 RMB loss before intervention,the differences were statistically significant(P<0.05).CONCLUSIONS:Clinical pharmacists'intervention on the application of edaravone and dexborneol concentrated solution for injection in patients with stoke has higher positive effect,which can reduce the occurrence of irrational medical orders and adverse drug reactions,relieve the economic burden of patients to a certain extent,and play a positive role in cost control of hospitals under the DRG payment model.
关键词
药师干预/脑卒中/依达拉奉右莰醇/疾病诊断相关分组付费
Key words
Pharmacists intervention/Stroke/Edaravone dexborneol/Diagnosis-related groups payment