淡紫紫孢菌引起角膜溃疡1例
A case of corneal ulcer caused by Purpureocillium lilacinum
王梦珍 1曾娇 2李丁丁 1谢秀丽 1刘亚丽 1李晓燕 3窦红涛 1徐英春1
作者信息
- 1. 中国医学科学院北京协和医学院北京协和医院检验科,北京 100730
- 2. 成都市第七人民医院检验科,成都 610044
- 3. 北京市房山区良乡医院检验科,北京 102401
- 折叠
摘要
患者,男,24岁,2022年9月16日因"右眼畏光、痒、视物不清"1个月余,门诊就诊,右眼有人工晶体的植入,此次受外伤后结膜混合充血,角膜中央溃疡,上皮大疱样改变.角膜溃疡组织标本分离培养出丝状真菌,经质谱鉴定为淡紫紫孢菌,并经rDNA ITS序列测定证实.予伏立康唑抗真菌治疗有效,病情好转,予以出院.
Abstract
The patient was a 24-years-old male,due to"photophobia,itching,and unclear vision in the right eye"for more than a month,he received outpatient treatment on September 16,2022,The right eye was implanted with an artificial lens before.After this trauma,the conjunctiva was mixed with congestion,central corneal ulcer,and epithelial bullous changes.Filamentous fung isolated from corneal ulcer tissue samples was identified as Purpureocillium lilacinum by mass spectrome-try,and been confirmed by rDNA ITS sequencing.Antifungal therapy with voriconazole was effective.When the condition improved,the patient was discharged.
关键词
淡紫紫孢菌/角膜溃疡/伏立康唑Key words
Purpureocillium lilacinum/corneal ulcer/voriconazole引用本文复制引用
基金项目
北京协和医院沉淀整合基金(ZC201905334)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据