Spinal Candida albicans infection:A case report and literature review
A 32-year-old male patient was admitted to the hospital because of'examination revealed costochondral joints and spinal multiple bone destruction for four months'.Four months ago,the patient was admitted to the oncology depart-ment of our hospital for ileostomy surgery with ileum restoration.After thorough examination,it was found thatcostochon-dral joints and spinal multiple bone destruction,and ultrasound guided needle biopsy of costochondral joints was performed.The pathological consideration was chronic suppurative infection,but no treatment was performed.One month before admis-sion,the range of costochondral joints and spinal bone damage increased during reexamination.Ultrasound guided needle bi-opsy of costochondral joints was performed again,Mycobacterium tuberculosis DNA testing was sent,and the result was negative.After surgery,DNA test results for Mycobacterium tuberculosis were negative.This time,the symptoms of low back pain gradually worsened,physical examination of lumbar,sacral midline and paravertebral tenderness,lumbar flexion and extension activities were limited,and the movement,sensation and reflexes of both lower limbs were normal.CT-guided lumbar needle biopsy were completed to confirm the diagnosis of Candida albicans infection.Fluconazole intravenous drip for three weeks,and then changed to oral drug treatment.After 8 weeks,there was a significant improvement in the symp-toms of lower back pain upon reexamination.Magnetic resonance imaging showed a reduction in vertebral bone and interver-tebral disc destruction.The condition improved significantly and was under follow-up.
万方数据
维普
