A case of infective Scedosporium apiospermum meningitis caused by head trauma was reported.Fungal culture and morphological observation were carried out in the positive culture medium of cerebrospinal fluid.The strain was identi-fied by the matter-assisted laser desorption ionization time-of-flight mass spectrometery.The internal transcribed spacer was sequenced and homologous analysis was performed.The strain was identified to be Scedosporium apiospermum.The results of E-test in vitro showed that the strain was sensitive to voriconazole.After 3 days of treatment with voriconazole,the pa-tient's condition improved,but the treatment was abandoned due to brain death after sudden subarachnoid and brainstem hemorrhage.
维普
万方数据