Pulmonary infection caused by Nocardia cyriacigeorgica in a patient with bronchiectasis:a case report and literature review
To report a 64-year-old female patient with pulmonary infection caused by Nocardia cyriacigeorgica,who also had bronchiectasis,the history of pulmonary tuberculosis,and systemic lupus erythematosus(SLE).Her main clinical mani-festations were repeated coughand expectoration.At the initial stage,combined with the patient's chest CT,pulmonary in-fection was considered,but the patient's condition did not improve after the antibiotics treatment.The results of sputum smear,sputum culture,fungal culture,and other examinations were all negative.Tracheoscopy was performed,and the pa-tient's lavage fluid was subjected to mNGS to detect the pathogen as N.cyriacigeorgica.After treatment with TMP-SMX and ampicillin sodium and sulbactam sodium,the patient recovered and discharged from hospital.After discharge,continue to take TMP-SMX and levofloxacin tablets.After more than 2 months of re-examination,the lesion of chest CT showed sig-nificant absorption.