首页|1991-2020年浙江省嘉善县结直肠癌生存分析

1991-2020年浙江省嘉善县结直肠癌生存分析

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[目的]分析1991-2020年浙江省嘉善县结直肠癌患者的生存情况.[方法]收集浙江省嘉善县1991年1月1日至2020年12月31日期间新发的结直肠癌病例,随访日期截至2023年12月.以5年为1组,采用寿命表法和Ederer Ⅱ法分别计算观察生存率和相对生存率,相对生存标化采用国际癌症生存标准进行调整.采用Joinpoint回归模型计算平均年度变化百分比(average annual percentage change,AAPC),分析各类结直肠癌生存率在1991-2020年期间的变化趋势.[结果]1991-2020年浙江省嘉善县结直肠癌5年相对生存率从21.7%(1991-1995 年)上升至 73.4%(2016-2020 年),并呈逐年递增趋势(AAPC=4.6%,P<0.05).5年相对生存率在男性和女性分别从1991-1995年的17.7%和30.0%上升至2016-2020年的72.7%和74.3%,女性增幅(AAPC=4.3%)高于男性(AAPC=3.9%).各年龄组的结直肠癌5年相对生存率均呈逐年递增趋势,其中65~74岁年龄组的增幅最大(AAPC=4.9%);除75岁及以上年龄组外,其余年龄组5年相对生存率变化趋势均有统计学意义(P均<0.05).[结论]1991-2020年浙江省嘉善县结直肠癌5年生存率逐年提高,其中女性5年生存率增幅高于男性,65~74岁年龄组增幅最大.应对重点人群进行早诊早治筛查,提高结直肠癌生存率.
Survival Analysis of Colorectal Cancer in Jiashan County,Zhejiang Province from 1991 to 2020
[Purpose]To analyze the survival of colorectal cancer patients in Jiashan County of Zhejiang Province from 1991 to 2020.[Methods]The data of newly reported cases of colorectal cancer were collected in Jiashan County from January 1,1991 to December 31,2020,and pa-tients were followed-up till December 2023.The observed survival rate(OSR)and relative survival rate(RSR)were calculated using the life table and Ederer Ⅱ method with 5-year intervals.Rela-tive survival was adjusted using the International Cancer Survival Standards.The Joinpoint re-gression model was used to calculate the average annual percentage change(AAPC)to analyze the change trend of survival rate.[Results]The 5-year RSR of colorectal cancer increased from 21.7%during 1991 to 1995 to 73.4%during 2016 to 2020,showing an increasing trend(AAPC=4.6%,P<0.05),for men it increased from 17.7%to 72.7%and for women it increased from 30.0%to 74.3%,with AAPCs of 3.9%and 4.3%,respectively(P<0.05).The 5-year RSR of colorectal can-cer in all age groups showed an increasing trend(P<0.05 for all age groups,except for 75+),and the highest increase was found in the age group of 65~74 years old(AAPC=4.9%).[Conclusion]From 1991 to 2020,the 5-year survival rate of colorectal cancer in Jiashan County showed a steady increase,for women and those aged 65~74 years old the increase was more significant.The cancer screening of high-risk groups should be focused on to improve colorectal cancer survival rate.

colorectal cancerobserved survival raterelative survival rateZhejiang

薛峰、费兴林、孙晶、张泽鹏、张瞾慧

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浙江省嘉善县肿瘤防治所,浙江嘉善 314100

浙江大学医学院,浙江 杭州 310058

结直肠癌 观察生存率 相对生存率 浙江

2025

中国肿瘤
中国医学科学院(全国肿瘤防治研究办公室)

中国肿瘤

北大核心
影响因子:2.414
ISSN:1004-0242
年,卷(期):2025.34(1)