辐射和儿童及青少年甲状腺癌的关系研究进展
Research progress on the relationship between radiation and thyroid cancer in chil-dren and adolescents
胡传祥 1郑向前1
作者信息
- 1. 天津医科大学肿瘤医院甲状腺颈部肿瘤科,国家恶性肿瘤临床医学研究中心,天津市"恶性肿瘤"临床医学研究中心,天津市肿瘤防治重点实验室(天津市 300060)
- 折叠
摘要
儿童及青少年甲状腺癌是一种少见的恶性肿瘤,病因学、临床病理特征及预后与成人甲状腺癌不同,发病率逐年上升.儿童及青少年相较成人对辐射更加敏感,辐射是导致儿童及青少年甲状腺癌较为肯定的危险因素之一.辐射的主要来源包括核事故和医疗辐射.本文对于辐射和儿童及青少年甲状腺癌发病的关系进行综述,以期提高重视辐射对于儿童及青少年甲状腺健康的危害.
Abstract
Pediatric and adolescent thyroid cancer is a rare malignant tumor with etiology,clinical-pathological features,and prognosis dif-fering from adult thyroid cancer,exhibiting an increasing incidence over the years.Compared to adults,children and adolescents are more sensitive to radiation,making it a definite risk factor for the development of thyroid cancer in this population.Radiation primarily originates from nuclear accidents and medical exposure.This review comprehensively explores the molecular changes induced by radiation leading to thyroid cancer in children and adolescents,aiming to raise awareness of the hazards posed by radiation to the thyroid health of this specific age group.The in-depth analysis provided in this medical review serves as a valuable reference for gaining insights into the disease mechan-ism and guiding future research endeavors.
关键词
儿童/青少年/甲状腺癌/辐射Key words
child/adolescent/thyroid cancer/radiation引用本文复制引用
基金项目
国家自然科学基金面上项目(82172821)
天津市医学重点学科(专科)建设项目(TJYXZDXK-009A)
出版年
2024