Efficacy comparison between two different medications in the treatment of otomycosis
Objective To compare the therapeutic efficacy between triamcinolone acetonide and econazole nitrate cream and 3%boric acid alcohol ear drops by local applying in the treatment of otomycosis.Methods A total of 124 patients with otomycosis treated in our hospital,from Feb 2019 to May 2022,were randomly divided into group A(GA)and group B(GB),with 62cases in each.Cases in GA were treated by triamcinolone acetonide and econazole nitrate cream applied into the ear canal under otoscope,those in GB were treated by 3%boric acid alcohol ear drops applied into the ear canal by patients themselves,for a continuous therapeutic course lasted for 3 weeks respectively.Then,the therapeutic efficacy was compared by the end of therapeutic course,with all these patients followed up for 3 months after the therapy.Results For the therapeutic effects of these therapies on the commonly seen symptoms among these cases,the improved levels of itching in ear,the feeling of aural fullness,ear discharge,skin red and swollen of the external canal and mold plaque in the canal,were shown more effective on the cases in GA than those in GB,while the improved amplitudes in hearing loss and otalgia were shown almost the comparative effect on cases in both groups.The total effective rates were 88.7%and 69.4%for GA and GB respectively flowing a course of treatment lasted for one week,they were 95.72%and 75.8%respectively by the end of a course of treatment lasted for two weeks,and they were 100%and 80.6%for both groups respectively by the end of the therapeutic course lasted for three weeks,all being obviously statistical significance(PP<0.05).By the end of following up period lasted for 3 months,the recurrence rates of both groups were 6.5%and 11.3%respectively,with no markedly statistical significance(P<0.05).Conclusion Local use of triamcinolone acetonide and econazole nitrate cream should be much effective than that of boric acid alcohol ear drops for the treatment of otomycosis.
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