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喉白斑的窄带成像内镜下诊断与病理分析

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目的 探讨通过窄带成像(narrow band imaging,NBI)电子喉镜下观察喉黏膜上皮内的毛细血管袢形态,能否指导喉白斑患者治疗方法的选择.方法 选取 2019 年 6 月~2021 年 9 月临床诊断为喉白斑的 68 例患者为研究对象,根据NBI电子喉镜的诊断结果,将患者分为两组:良性病变组(52/68)和恶性病变组(16/68).比较NBI喉镜诊断与病理检查结果的一致性.结果 良性病变组中病理确诊为鳞状上皮增生伴角化 35 例(67.31%),轻度不典型增生 9 例(17.31%),中度不典型增生 3 例(5.77%),原位癌 5 例(9.62%),恶性病变组中病理确诊为中度不典型增生 2 例(12.50%),重度不典型增生 1 例(6.25%),原位癌 9 例(56.25%),浸润癌 4例(25.00%).采用Kappa一致性检验法,k=0.687,P<0.001,说明NBI电子喉镜诊断结果和病理检查结果存在一致性.结论 NBI电子喉镜能很好的分辨喉白斑的性质,对喉白斑治疗方法的选择和随访观察喉白斑的进展有较高的指导意义.
Correlation analysis of narrow band imaging laryngoscope diagnosis and pathology in laryngeal leukoplakia
Objective To explore whether the narrow band imaging(NBI)electronic laryngoscope observe intraepithelial capillary loops of laryngeal mucosal can guide the selection of treatment methods for patients with laryngeal leukoplakia.Methods Clinical data of 68 patients with laryngeal leukoplakia from June 2019 to September 2021 were selected as the research object.According to the diagnostic results of NBI electronic laryngoscope,the patients were divided into two groups:benign lesion group(52/68)and malignant lesion group(16/68).The consistency of NBI laryngoscopy diagnosis and pathological examination was compared.Results In the benign lesion group,the pathological diagnoses included 35 cases(67.31%)of squamous epithelial hyperplasia with keratosis,9 cases(17.31%)of mild atypical hyperplasia,3 cases(5.77%)of moderate atypical hyperplasia and 5 cases(9.62%)of carcinoma in situ.In the malignant lesion group,there were 2 cases(12.50%)of moderate atypical hyperplasia,1 case(6.25%)of severe atypical hyperplasia,9 cases(56.25%)of carcinoma in situ and 4 cases of invasive carcinoma(25.00%).Kappa consistency test was used,k=0.687,P<0.001,indicating that the diagnosis of NBI electronic laryngoscope were consistent with pathological diagnosis.Conclusions NBI electronic laryngoscope can well distinguish the nature of laryngeal leukoplakia,and has high guiding significance for the selection of treatment methods and the follow-up observation of the progress of laryngeal leukoplakia.

laryngeal leukoplakianarrow band imagingelectronic laryngoscopepathology

梁锦辉、黄梅、高山、黄河浪、庞礴、李莉、罗海林、张翔、林忠菊、毛渭东

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陕西省汉中市中心医院耳鼻咽喉头颈外科(723000)

陕西省汉中市中心医院病理科

喉白斑 窄带成像 电子喉镜 病理学

2024

中国中西医结合耳鼻咽喉科杂志
中国中西医结合学会

中国中西医结合耳鼻咽喉科杂志

CSTPCD
影响因子:0.7
ISSN:1007-4856
年,卷(期):2024.32(1)
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