首页|附子理中丸方治疗溃疡性结肠炎的研究进展

附子理中丸方治疗溃疡性结肠炎的研究进展

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附子理中丸方是治疗呕吐泄泻等消化道疾病的常用中药,现代药理研究表明其具有抗炎、调节免疫、修复胃肠黏膜屏障、镇痛等作用,在临床上主要用于胃溃疡、溃疡性结肠炎、慢性腹泻等脾肾阳虚所致的消化道疾病的治疗。溃疡性结肠炎是临床常见的消化道疾病之一,且近年来发病率逐渐升高,由于其具有病程长、难治愈、易反复发作的特点,严重影响患者的生命质量,目前并没有特效的治疗药物。临床研究表明,附子理中丸方对溃疡性结肠炎具有一定的疗效,本文将从临床应用、药理作用与活性成分3个方面对附子理中丸方治疗溃疡性结肠炎的作用进行综述,为其进一步开发应用提供依据。
Research progress in the treatment of ulcerative colitis by Fuzi Lizhong Prescription
Traditional Chinese Medicine,such as Fuzi Lizhong Prescription,is frequently used to treat diges-tive system disorders including vomiting and diarrhea.It possesses anti-inflammatory,immune-regulating,gas-trointestinal mucosal barrier repair,analgesic,and other effects,according to contemporary pharmacological in-vestigations.It is primarily utilized in the therapeutic therapy of gastrointestinal tract disorders brought on by chronic diarrhea,ulcerative colitis,gastric ulcers,and various spleen and kidney Yang shortage.One of the fre-quent gastrointestinal disorders seen in clinics is ulcerative colitis,whose prevalence has progressively risen in re-cent years.There is no particular medication for therapy since the disease has a protracted course,is difficult to treat,and is prone to recurrence.These factors substantially impair patients'quality of life.Clinical studies have demonstrated that Fuzi Lizhong Prescription can treat ulcerative colitis.In order to establish a foundation for its future research and use,this article investigated the clinical applicability,pharmacological activity,and active components of aconitum rhizome in the treatment of ulcerative colitis.

Fuzi Lizhong Prescriptionulcerative colitisactive ingredientsmechanism of action

李依林、左泽平、田颖颖、赵新月、刘闯、于尚玥、裴海鸾、田时秋、王志斌

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北京中医药大学中药学院(北京,102401)

北京同仁堂科技发展股份有限公司制药厂

附子理中丸方 溃疡性结肠炎 活性成分 作用机制

2024

中国中西医结合消化杂志
华中科技大学同济医学院,中国中西医结合学会消化系统疾病专业委员会,中华中医药学会脾胃病专业委员会

中国中西医结合消化杂志

CSTPCD
影响因子:1.363
ISSN:1671-038X
年,卷(期):2024.32(1)
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