中国中西医结合消化杂志2024,Vol.32Issue(1) :78-83.DOI:10.3969/j.issn.1671-038X.2024.01.15

附子理中丸方治疗溃疡性结肠炎的研究进展

Research progress in the treatment of ulcerative colitis by Fuzi Lizhong Prescription

李依林 左泽平 田颖颖 赵新月 刘闯 于尚玥 裴海鸾 田时秋 王志斌
中国中西医结合消化杂志2024,Vol.32Issue(1) :78-83.DOI:10.3969/j.issn.1671-038X.2024.01.15

附子理中丸方治疗溃疡性结肠炎的研究进展

Research progress in the treatment of ulcerative colitis by Fuzi Lizhong Prescription

李依林 1左泽平 2田颖颖 1赵新月 1刘闯 1于尚玥 1裴海鸾 1田时秋 1王志斌2
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作者信息

  • 1. 北京中医药大学中药学院(北京,102401)
  • 2. 北京同仁堂科技发展股份有限公司制药厂
  • 折叠

摘要

附子理中丸方是治疗呕吐泄泻等消化道疾病的常用中药,现代药理研究表明其具有抗炎、调节免疫、修复胃肠黏膜屏障、镇痛等作用,在临床上主要用于胃溃疡、溃疡性结肠炎、慢性腹泻等脾肾阳虚所致的消化道疾病的治疗.溃疡性结肠炎是临床常见的消化道疾病之一,且近年来发病率逐渐升高,由于其具有病程长、难治愈、易反复发作的特点,严重影响患者的生命质量,目前并没有特效的治疗药物.临床研究表明,附子理中丸方对溃疡性结肠炎具有一定的疗效,本文将从临床应用、药理作用与活性成分3个方面对附子理中丸方治疗溃疡性结肠炎的作用进行综述,为其进一步开发应用提供依据.

Abstract

Traditional Chinese Medicine,such as Fuzi Lizhong Prescription,is frequently used to treat diges-tive system disorders including vomiting and diarrhea.It possesses anti-inflammatory,immune-regulating,gas-trointestinal mucosal barrier repair,analgesic,and other effects,according to contemporary pharmacological in-vestigations.It is primarily utilized in the therapeutic therapy of gastrointestinal tract disorders brought on by chronic diarrhea,ulcerative colitis,gastric ulcers,and various spleen and kidney Yang shortage.One of the fre-quent gastrointestinal disorders seen in clinics is ulcerative colitis,whose prevalence has progressively risen in re-cent years.There is no particular medication for therapy since the disease has a protracted course,is difficult to treat,and is prone to recurrence.These factors substantially impair patients'quality of life.Clinical studies have demonstrated that Fuzi Lizhong Prescription can treat ulcerative colitis.In order to establish a foundation for its future research and use,this article investigated the clinical applicability,pharmacological activity,and active components of aconitum rhizome in the treatment of ulcerative colitis.

关键词

附子理中丸方/溃疡性结肠炎/活性成分/作用机制

Key words

Fuzi Lizhong Prescription/ulcerative colitis/active ingredients/mechanism of action

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出版年

2024
中国中西医结合消化杂志
华中科技大学同济医学院,中国中西医结合学会消化系统疾病专业委员会,中华中医药学会脾胃病专业委员会

中国中西医结合消化杂志

CSTPCD
影响因子:1.363
ISSN:1671-038X
参考文献量33
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