Research progress on the mechanism of Traditional Chinese Medicine regulating intestinal function in the treatment of hepatocellular carcinoma based on the gut liver axis
Primary liver carcinoma is one of the malignant tumors with high incidence rate and mortality in the world,of which hepatocellular carcinoma accounts for more than 90％.The intestine and liver communicate through bidirectional connections between the portal vein,bile duct,and systemic circulation,and the gut liver ax-is becomes an important link in the pathogenesis of hepatocellular carcinoma.Intestinal barrier dysfunction and dysbiosis of gut microbiota are important factors in the occurrence of hepatocellular carcinoma.Traditional Chi-nese Medicine has a history of thousands of years in clinical application.Based on the theory of the gut liver axis,Traditional Chinese Medicine can effectively block the gut liver signal in the prevention and treatment of hepatocel-lular carcinoma,which is of great significance for precise prevention and treatment of hepatocellular carcinoma.This article summarizes the regulatory and intervention effects of Traditional Chinese Medicine and its active ingre-dients on hepatocellular carcinoma based on the theory of visceral organs and the theory of gut liver axis,hoping to provide new strategies and ideas for further clinical prevention and treatment of hepatocellular carcinoma.
Traditional Chinese Medicinegut liver axisintestinal barrierhepatocellular carcinoma
万方数据
维普
