Non antibiotic alternative treatments for Helicobacter pylori infection
The global prevalence of Helicobacter pylori(H.pylori)infection remains high.H.pylori infec-tion is associated with many kinds of diseases.Antibiotic treatment is the main treatment therapy for H.pylori infection.Antibiotics may lead to bacterial resistance,imbalance of the host's gastrointestinal microbiota,etc.Some patients may not suitable for antibiotic treatment due to various reasons.It is difficult to successful eradicate through antibiotics for patients with multiple antibiotics resistant H.pylori infection,and this has become a chal-lenge in the era of antibiotic resistance.Improving patient symptoms or adjuvant antibiotic therapy through non antibiotic alternative therapy has been a hot topic in recent years.This review will focus on alternative therapies such as immunity,probiotics,natural products,Chinese herbal medicine,bacteriophages,and phototherapy in the applications and possible mechanisms in the treatment of H.pylori infection.