Clinical observation on the combination of traditional Chinese medicine internal injection and external application therapy with Western medicine routine treatment for damp heat and stasis syndrome in acute pancreatitis
Objective:To observe the clinical efficacy of traditional Chinese medicine internal injection and ex-ternal application combined with conventional Western medicine in the treatment of damp heat stasis syndrome in acute pancreatitis(AP)and explore its possible mechanism.Methods:Sixty-four AP patients who visited our hos-pital were selected as the research subjects.Using a random number table method,the patients were divided into two groups:the treatment group and the control group,with 32 cases in each group.The control group received routine symptomatic treatment with Western medicine for 7 days.The treatment group patients were treated with traditional Chinese medicine injection and external application(gastric tube injection of Qingyi Tongfu Formula and Jiawei Dachengqi Formula acupoint application)based on conventional Western medicine treatment for 7 days.Compare the scores of traditional Chinese medicine symptoms(abdominal pain,bitter mouth),physical signs(bloating,defecation),acute physiological function,and chronic health status evaluation system Ⅱ(APACHEⅡ)between two groups of patients,and evaluate the efficacy of traditional Chinese medicine syndromes.Bio-chemical indicators were measured before and on the 7th day of treatment,including blood amylase(AMS),urine amylase(UAMY),serum lipase(LPS),and inflammation indicator C-reactive protein(CRP)levels.Results:The total clinical effective rate of the treatment group was 93.75％,significantly higher than that of the control group at 81.25％,with a statistically significant difference(P＜0.05).After treatment,the APACHE Ⅱ,abdominal pain,defecation,bloating,and bitterness scores in the treatment group improved significantly compared to before treatment and the control group(P＜0.05).Compared with before treatment and the control group,the levels of AMS,UAMY,LPS,and CRP in the treatment group significantly decreased,with statistical significance(P＜0.05).Conclusion:Combining traditional Chinese medicine internal injection and external application with West-ern medicine routine treatment can inhibit inflammatory reactions in patients with AP damp heat stasis syndrome,effectively improve gastrointestinal function,alleviate clinical symptoms,and is worth learning from.
acute pancreatitisQingyi Tongfu Formuladamp heat stasis syndrometraditional Chinese medicine internal injection and external application therapyJiawei Dachengqi Formula
万方数据
维普
