首页|中医诊治克罗恩病的临床研究进展

中医诊治克罗恩病的临床研究进展

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克罗恩病(CD)是一种病因未明、可累及全消化道的特发性炎症性疾病,本病病程迁延反复,以腹痛、腹泻、瘘管形成等为主要症状。目前西医治疗存在治疗达标率低、复发率较高、不良反应较多等不足。中医诊治CD尚处于起步阶段,研究发现中医药在缓解症状、抑制炎症反应、改善凝血功能、促进黏膜愈合、提高生物制剂临床应答率、减少复发率及治疗肛周并发症等方面具有作用。本文对近10年来中医对CD的病因病机的认识、中医辨证分型和中医治疗的文献进行综述。
Clinical research progress on traditional Chinese medicine diagnosis and treatment of Crohn's disease
Crohn's disease(CD)is an idiopathic inflammatory disease of undetermined etiology that can in-volve the entire digestive tract.It presents recurrent or persisting abdominal pain,diarrhea,or fistula as the main symptoms.There are many deficiencies such as lower treat-to-target rate,higher relapse rate,and higher intoler-ance rate in Western medicine treatment on CD.Traditional Chinese medicine(TCM)treatment on CD is still in its infancy.It has been reported that TCM could be effective in relieving symptoms,inhibiting inflammation,im-proving coagulation function,promoting mucosal healing,increasing the clinical response rate of biologics,reduc-ing recurrence rate,and treating perianal complications.The literature in recent 10 years related to TCM etiology and pathogenesis,TCM syndrome differentiation and TCM treatment on CD has been reviewed.

Crohn's diseaseetiology and pathogenesistraditional Chinese medicine syndrome differentia-tiontraditional Chinese medicine treatment

姚钧仁、刘育辰、单静怡、林江

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上海中医药大学附属龙华医院脾胃病科(上海,200032)

克罗恩病 病因病机 中医证型 中医治疗

国家自然科学基金海派中医流派传承创新团队建设项目上海市进一步加快中医药传承创新发展三年行动计划(2020-2023)

821047432021LPTD-009ZY2021-2023-0207-01

2024

中国中西医结合消化杂志
华中科技大学同济医学院,中国中西医结合学会消化系统疾病专业委员会,中华中医药学会脾胃病专业委员会

中国中西医结合消化杂志

CSTPCD
影响因子:1.363
ISSN:1671-038X
年,卷(期):2024.32(5)