The renaming of non-alcoholic fatty liver disease(NAFLD)to metabolic dysfunction-associated fatty/steatotic liver disease(MAFLD/MAFLD)has been controversial for the last two years,during which the re-sults of big data studies have proved the age-old limitations of NAFLD.Revisiting the nomenclature will allow for a proper understanding of the key causative factors of NAFLD,and an appreciation of its heterogeneity and differ-ent clinical phenotypes.The clinical response rate of NAFLD drug therapy is not high.By analyzing its heteroge-neity and combining it with the theory of"different treatment for the same disease"in traditional Chinese medi-cine,we can provide references for clinical diagnosis,research,and treatment of NAFLD.
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