Exploring the role of the small intestine in the pathogenesis of functional dyspepsia based on the correlation of stomach-small intestine-spleen
Functional dyspepsia(FD)is a common clinical functional gastrointestinal disease.Traditional Chi-nese medicine(TCM)believes that its basic pathogenesis is spleen deficiency and Qi stagnation,failure of stomach Qi to a descendand disturbance in ascending and descending of middle jiao.The small intestine is the central link of the spleen ascending and the stomach descending.The functions of the small intestine in"containing and diges-ting"and"separating the clear from the turbid"are closely associated with the process of the spleen raising the clear and the stomach lowering the turbid.If the functions of the small intestine are abnormal,it will affect the rise and fall of the spleen and stomach Qi,and the middle jiao is unfavorable,which will eventually lead to the oc-currence of FD.The understanding of small intestine function in TCM is based on human anatomy combined with clinical practice,and the function of the small intestine is also dependent on the organization of the human anato-my.Thus,when there are abnormal changes in the duodenum in Western medicine,such as when the duodenal viscera are hypersensitive and the intestinal mucosal barrier is impaired,the physiological functions of the small intestine"containing and digesting"and"separating the clear from the turbid"in Chinese medicine will also be af-fected,which in turn will easily induce or lead to FD.TCM can have positive therapeutic effects on FD by regula-ting duodenal hypersensitivity and intestinal mucosal barrier function.Therefore,exploring the role of the small intestine in the pathogenesis of FD based on the link between the stomach,small intestine,and spleen provides a new idea and theoretical basis for the prevention and treatment of FD.
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