Research progress on experimental mechanism of traditional Chinese medicine treatment of chronic atrophic gastritis
Chronic atrophic gastritis(CAG)is a common disease of digestive system,which has the character-istics of long course,frequent recurrence,difficult to cure and easy to become cancerous.At present,its patho-genesis is not clear,Western medicine believes that it is related to Helicobacter pylori(Hp)infection,immunity,bile and duodenal reflux,genetics and other factors.The treatment is mainly to kill Hp,promote gastrointestinal motility,and inhibit gastric acid,which has a certain effect on improving symptoms,but it is difficult to reverse pathology and prevent the transformation of inflammation to cancer.TCM treatment is based on syndrome differ-entiation and has shown great advantages in the treatment of CAG through TCM,acupuncture and other treatment methods.Through the review of relevant experimental research literature on the treatment of CAG by traditional Chinese medicine,it is found that traditional Chinese medicine has excellent efficacy in alleviating CAG inflamma-tion,repairing damaged gastric mucosa,and blocking the transformation of gastric mucositis to cancer.This is mainly related to the effective improvement of inflammatory microenvironment,regulation of programmed death,anti-oxidative stress,repair of gastric mucosal damage,improvement of gastric mucosal metabolism and regula-tion of gastrointestinal hormone release by traditional Chinese medicine,acupuncture and moxibustion,etc.This paper summarizes from the above six aspects,in order to provide reference for the research on the progress of rel-evant mechanisms of TCM treatment of CAG.
chronic atrophic gastritisinflammation-cancer transformationChinese medicineacupuncturemechanism of action
万方数据
维普
