Research progress of mechanism about Jinghua Weikang capsule against Helicobacter pylori
Helicobacter pylori(HP)is a kind of bacteria that plays a serious threat to human health in the world,with a high global infection rate and high drug resistance.Jinghua Weikang capsule has got certain clinical effect in the treatment of HP,but its mechanism is still unknown.The results showed that Jinghua Weikang cap-sule anti-HP mainly by affecting NF-κB signaling pathway.It can inhibit the formation of HP biofilm then im-prove the efficiency of antibiotics,also can reduce the minimum inhibitory concentration of antibiotics,and cooper-ate with antibiotics to.eradicate HP and reverse antibiotic resistance.It can also improve the intestinal flora struc-ture after HP infected,increase the abundance of beneficial flora and decrease the number of harmful flora.It can also repair the damaged gastric mucosa after HP infected and restore the morphology of gastric mucosal epithelial cells to normal.In this paper,we will review the mechanism of Jinghua Weikang capsules against HP in detail.
Jinghua Weikang capsuleChenopodium ambrosioides LAdina rubella HanceHelicobacter py-lorimechanism