Research progress of fecal microbiota transplantation for hepatic encephalopathy
Hepatic encephalopathy is a syndrome based on metabolic disorders,causing central nervous sys-tem dysfunction.Due to the abnormal function of the gut-liver-brain axis,hepatic encephalopathy can cause chan-ges in the intestinal flora and its metabolites,intestinal permeability and microbiotal translocation leading to sys-temic and local inflammation,further affecting the function of the liver and nervous system.Fecal microbiota transplantation is an emerging special type of organ transplantation in which involves transplanting normal func-tional microbiota in feces into the intestinal tract of patients aimed at helping restore the balance of intestinal flora by reconstructing intestinal flora structure and adjusting metabolic processes and signaling pathways in vivo.This article reviews the mechanism and research progress of fecal microbiota transplantation in the treatment of hepatic encephalopathy.
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