门静脉肝窦血管病临床病理特征及研究进展
Clinicopathological features and new advancement of porto-sinusoidal vascular disease
董思晗 1赵新颜2
作者信息
- 1. 首都医科大学基础医学院(北京,100069)
- 2. 首都医科大学附属北京友谊医院肝病中心
- 折叠
摘要
门静脉肝窦血管病(porto-sinusoidal vascular disease,PSVD)是一种以门静脉高压为特征的肝血管疾病,近年来PSVD确诊病例数量逐年增加.通过回顾近期文献,本综述旨在阐述从特发性非肝硬化性门静脉高压到PSVD的概念变迁;介绍PSVD的主要病理特征及鉴别诊断要点;介绍无创性筛查方法,如腹部影像和瞬时弹性成像特征;探讨与PSVD相关的免疫因素、药物及遗传疾病等相关因素;还介绍了 PSVD目前的治疗进展,并对其不同预后进行描述.未来需要更多研究以明确其致病机制及探索新的治疗方法.
Abstract
Porto-sinusoidal vascular disease(PSVD)is a hepatic vascular disease characterized by portal hy-pertension.In recent years,the number of confirmed cases of PSVD has been increasing annually.This review aims to summarize the evolution of the concept from idiopathic non-cirrhotic portal hypertension to PSVD,high-light the main pathological features of PSVD,and discuss key points for differential diagnosis.The review also discusses non-invasive diagnostic approaches,including abdominal imaging and transient elastography,and ex-plores factors related to PSVD,including immune factors,medications,and genetic diseases.In addition,the cur-rent treatment progress and its different prognosis are introduced.Future research is needed to clarify the underly-ing pathogenic mechanisms and explore new treatment approaches for PSVD.
关键词
门静脉肝窦血管病/病理特征/诊断/预后Key words
porto-sinusoidal vascular disease/pathological features/diagnosis/prognosis引用本文复制引用
出版年
2024
NETL
NSTL
万方数据