首页|剪切波弹性成像技术对低强度脉冲超声刺激足三里穴引起肌张力变化的评估

剪切波弹性成像技术对低强度脉冲超声刺激足三里穴引起肌张力变化的评估

Value of shear wave elastography in evaluation to muscular tension change caused by stimulation at Zusanli acupoint by low-intensity pulsed ultrasound

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目的:应用剪切波弹性成像技术(SWE)评估低强度脉冲超声(LIPUS)刺激足三里穴位时肌张力的变化特点,初步探讨LIPUS刺激穴位的可行性,以期为LIPUS在外周神经调控研究中提供定量评估信息.方法:实验动物为16只雄性SD大鼠,随机分为胫骨前肌组和腓肠肌组各8只,应用LIPUS刺激大鼠足三里穴20 min,通过SWE连续监测胫骨前肌和腓肠肌的肌张力变化.酶联免疫吸附试验(ELISA)测定刺激前后血清5-羟色胺(5-HT)水平变化.结果:胫骨前肌在LIPUS刺激足三里穴后3 min的剪切波速度和杨氏模量值均较刺激前显著升高(均P<0.05);腓肠肌在刺激足三里穴后13、14 min的剪切波速度和杨氏模量值均较刺激前显著升高(均P<0.001).血清5-HT水平较刺激前显著升高(P<0.05).结论:SWE可为评估LIPUS刺激足三里穴位引起的肌张力变化提供客观依据,为LIPUS的经穴效应的研究提供更多信息.
Objective:To explore the value and feasibility of shear wave elastography(SWE)in the evaluation to the musclar tension change during stimulation of Zusanli acupoint by low-intensity pulsed ultrasound(LIPUS),with a view to providing quantitative assessment information for LIPUS in the study of peripheral neuromodulation.Methods:A total of 16 SD rats were randomly divided into two groups,the tibialis anterior muscle group(8 rats)and the gastrocnemius muscle group(8 rats).LIPUS was applied to stimulate Zusanli acupoint of the rats for 20 min,and the tension changes of tibialis anterior muscle and gastrocnemius muscle were continuously monitored by SWE.The differences in 5-HT levels before and after stimulation were determined.Results:Compared before stimulation,the shear wave velocity(SWV)and Young's modulus of the tibialis anterior muscle were significantly higher at 3 min after LIPUS stimulation(both P<0.05),and those of the gastrocnemius muscle were significantly higher at 13 and 14 min after LIPUS stimulation(both P<0.001).Serum 5-HT level was significantly higher than before stimulation(P<0.05).Conclusions:SWE can provide an objective basis for evaluating the changes in muscle tension induced by LIPUS stimulation of Zusanli acupoint,and provide a richer information for the study of meridian effect by LIPUS.

Shear wave elastographyUltrasonographyPoint ST36(Zusanli)De qi5-Hydroxytryptamine

韩镍、单佳丽、陆玲玲、汪倩妮、金琳

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上海中医药大学附属光华医院超声科,上海 200052

上海体育大学运动健康学院,上海 200438

上海健康医学院附属嘉定区中心医院超声科,上海 201800

剪切波弹性成像 超声检查 穴,足三里 得气 5-羟色胺

2024

中国中西医结合影像学杂志
中国中西医结合学会,山东中医药大学附属医院

中国中西医结合影像学杂志

CSTPCD
影响因子:0.857
ISSN:1672-0512
年,卷(期):2024.22(1)
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