Objective:To investigate the correlation between hypertension and clear cell renal cell carcinoma(ccRCC).Methods:The data from 164 ccRCC patients and 58 healthy controls were collected.The ccRCC patients with a history of hypertension of 3 years or more composed the hypertension group(57 cases),and the ccRCC patients who had never been diagnosed with hypertension composed the non-hypertension group(107 cases).The ADC and rADC values of tumor,the contralateral healthy kidney and the control group were measured and calculated,and relevant data were analyzed by SPSS 24.0 software.Results:In the hypertension group,the ADC values of the tumors and the contralateral healthy kidney were(1.683±0.435)×10-3 and 2.047(0.373)×10-3 mm²/s,respectively,and the rADC value was 0.83±0.20.In the non-hypertension group,the ADC values of the tumors and the contralateral healthy kidney were(1.863±0.401)×10-3 and 2.011(0.290)×10-3 mm²/s,respectively,and the rADC value was 0.95±0.20.The ADC value of the tumors was significantly different between the hypertension group and the non-hypertension group(P=0.009),and the ADC value of the contralateral kidney wasn't significantly(P=0.136),the rADC value was significantly different(P=0.001).Conclusion:Hypertension is associated with a decrease in ADC value of ccRCC,which may increase tumor malignancy.
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