Objective:To explore the value of DWI combined with 3D arterial spin labeling(3D-ASL)in differentiating parasellar meningioma from cavernous hemangioma.Methods:MRI data of 20 patients with parasellar meningioma and 20 patients with cavernous hemangioma confirmed by surgery and pathology were analyzed retrospectively.The characteristics of plain scan,enhanced scan,DWI,3D-ASL images were analyzed,and the minimum ADC value(ADCmin)and the maximum relative cerebral blood flow(rCBF)were measured.Results:Parasellar meningiomas were round in shape and isointense on T2WI,with early moderate enhancement,peritumoral edema and meningeal tail sign in common.Parasellar meningiomas showed iso-and hyperintensity on DWI,and the ADCmin value ranged from 0.67×10-3 mm2/s to 1.12×10-3 mm2/s,with an average of(0.76±0.13)×10-3 mm2/s.And most of them showed hyperperfusion,and the maximum rCBF was 5.072～9.683,with an average of 7.062±3.571.Most cavernous hemangiomas were dumbbell-shaped and hyperintensity on T2WI,with significant fill-in enhancement in common,without peritumoral edema and meningeal tail sign.Cavernous hemangiomas showed hypointensity on DWI,and the ADCmin value ranged from 1.48×10-3 mm2/s to 1.83×10-3 mm2/s,with an average of(1.56±0.25)×10-3 mm2/s.And most of them showed hypoperfusion,and the maximum nCBF was 1.356～3.014,with an average of 1.696±1.028.There were significant differences in tumor morphology,T2WI and DWI signal,the ADCmin and rCBF values,enhancement pattern and perfusion between the two groups(all P<0.05).Conclusion:DWI combined with 3D-ASL has a high application value in the differential diagnosis of parasellar meningioma and cavernous hemangioma.
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