Objective:To evaluate the CT features of thyroid micro follicular hyperplastic nodule(FHN).Methods:The clinical and CT data of 69 patients with micro FHN(FHN group,109 lesions)and 77 patients with papillary thyroid microcarcinoma(PTMC group,90 lesions)were collected.The non-enhanced CT density,enhancement pattern,cystic degeneration,edge interruption,envelope sign and calcification were analyzed and compared between the two groups,and the diagnostic efficiencies were evaluated.Results:There were statistical significances in the non-enhanced CT density,enhancement pattern,cystic degeneration,edge interruption,envelope sign and calcification between the two groups(all P<0.05).The CT features with high positive predictive value included homogeneous iso-or high-density on non-enhanced CT(1.000),inhomogeneous density on non-enhanced CT(0.894),inhomogeneous enhancement(0.804)and cystic degeneration(0.838).The CT feature with high negative predictive value was absence of envelope sign(0.758).Conclusions:Homogeneous iso-or high-density or inhomogeneous density on non-enhanced CT,inhomogeneous enhancement,cystic degeneration and absence of envolpe sign are the significant CT features in diagnosing micro FHN.