首页|甲状腺微小乳头状癌微波消融术后疗效评估的影响因素分析

甲状腺微小乳头状癌微波消融术后疗效评估的影响因素分析

Analysis of influence factors of efficiency evaluation of microwave ablation in treatment of papillary thyroid microcarcinoma

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目的:探讨超声引导下微波消融治疗甲状腺微小乳头状癌(PTMC)的临床疗效及结节体积的影响因素.方法:纳入行微波消融治疗的低危PTMC患者63例,于术后1 d和1、3、6、12个月进行随访,对临床疗效及结节体积进行观察;根据结节吸收情况分为结节消失组(19例)与结节未消失组(43例),分析影响结节体积的相关因素.结果:63例均一次性完全消融成功,1例因颈部淋巴结转移转行外科手术.术后疼痛1例、出血2例、声音改变1例,对症处理后均恢复正常,无其他不良反应及并发症.微波消融后结节体积短时间内急剧增大,术后6个月时结节体积恢复至术前水平,19例结节术后12个月完全吸收,其中4例发生在术后6个月.2组在有无微小钙化灶、与最近被膜的距离、甲状腺影像报告和数据系统(TI-RADS)分类、术后1 d结节体积、消融时间、消融热量及性别方面差异均无统计学意义(均P>0.05);2组年龄、术前结节体积、单位体积能量差异均有统计学意义(均P<0.05).结论:超声引导下微波消融治疗低危PTMC的效果良好,安全性高.年轻患者、小病灶及单位体积能量高的患者微波消融术后结节吸收效果好.
Objective:To investigate the clinical efficiency of ultrasound-guided microwave ablation(MWA)in the treatment of papillary thyroid microcarcinoma(PTMC)and the influencing factors on nodule volume.Methods:63 low-risk PTMC patients with MWA treatment were collected and followed up 1 day,1,3,6,12 months after MWA,and their clinical efficiency and nodule volume were observed.According to the absorption of nodules,they were divided into the absorbed group(19 cases)and the unabsorbed group(43 cases),and the relevant factors affecting the volume of nodules were analyzed.Result:63 patients underwent complete ablation after MWA,and 1 patient underwent surgery due to cervical lymph node metastasis.After MWA,pain occurred in 1 patient,bleeding in 2 patients,and voice change in 1 patient,all of them recuperated after symptomatic treatment.And there were no other adverse reactions or complications.After MWA,the nodule volume increased sharply in a short time,and recovered to the preoperative level in 6 months after ablation,19 cases had complete nodule absorption in 12 months after ablation,among them,4 cases disappeared in 6 months after ablation.There were no significant differences in the microcalcification,distance from the nearest capsule,TI-RADS category,1-day postoperative nodule volume,ablation time,ablation heat or gender between the two groups(all P>0.05).There were significant differences in age,preoperative nodule volume and energy per unit volume between the two groups(all P<0.05).Conclusions:Ultrasound-guided MWA has a good efficiency and high safety in the treatment of low-risk PTMC.Young,small lesion and high energy per unit volume will have good nodule absorption after MWA.

Microwave ablationThyroid papillary carcinomaClinical efficacyAbsorption rate

邓伟、张英霞、闫诺、李昊昌

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内蒙古医科大学附属医院超声科,内蒙古 呼和浩特 010000

微波消融 甲状腺微小乳头状癌 临床疗效 吸收率

内蒙古自治区自然科学基金项目

2020MS08193

2024

中国中西医结合影像学杂志
中国中西医结合学会,山东中医药大学附属医院

中国中西医结合影像学杂志

CSTPCD
影响因子:0.857
ISSN:1672-0512
年,卷(期):2024.22(3)
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