Objective:To explore the predictive value of spectral CT parameters in synchronous brain metastasis of lung adenocarcinoma.Methods:A retrospective analysis was conducted on 107 patients with lung adenocarcinoma confirmed by pathology.All patients underwent cerebral MRI scan and were divided into the brain metastasis group(39 cases)and the non-metastasis group(68 cases).All patients underwent spectral CT plain and enhancement scans with reconstruction of spectral parameters such as 40,70 and 100 keV,iodine concentration and water concentration,and the slope of the energy spectrum curve(λHU)was calculated.The clinical data and spectral parameters between the two groups were compared.Results:EGFR mutation rate was statistically different between the two groups(P=0.003).There were no statistical differences in age or gender between the two groups(both P>0.05).The CT values of 40,70 and 100 keV images,λHU and iodine concentration in brain metastasis group were higher than those in the non-metastasis group(all P<0.05),while water concentration had no difference(P=0.100).The AUCs of CT values of 40,70 and 100 keV images,λHU and iodine concentration were 0.801,0.755,0.681,0.798,0.811,respectively,and iodine concentration had the highest efficiency.Conclusion:The spectral CT parameters have high clinical value in predicting synchronous brain metastasis of lung adenocarcinoma,which is helpful for clinical decision making.
万方数据
维普
