Debridement and Antibiotic-Loaded Calcium Sulfate Implantation for the Treatment of Clavicular Osteomyelitis
Objective:To investigate the efficacy of debridement and antibiotic-loaded calcium sulfate implantation for the treatment of clavicular osteomyelitis.Methods:Retrospective analyzed clinical data of 21 patients with clavicular osteomye-litis treated with debridement and antibiotic-loaded calcium sulfate implantation from January 2016 to June 2022.The oper-ation time,infection control,hospital stay,the presence of infection recurrence and complications were recorded,and the re-covery of shoulder function was assessed by visual analogue scale(VAS)score and Constant shoulder function score at the final follow-up.Results:All 21 patients underwent surgery successfully,and the operative time ranged from 55 to 150 min,with an average of(94.52±20.12)min.All patients were followed up for 13 to 37 months,with an average of(27.86±5.93)months.Serum inflammatory indexes such as erythrocyte sedimentation rate(ESR),white blood cells(WBC)and C-reactive protein(CRP)were reduced in patients at 7 d after surgery compared with preoperatively(P＜0.05).The swelling and pain of the affected area disap-peared basically at 2 weeks after surgery,and the surgical incision healed well.2 cases of recurrence of infection were cured after debridement with antibiotic-loaded calcium sulfate implantation again,with a recurrence rate of infection of 2/21 and none of them had pathological fractures.At the last follow-up,the VAS score and Constant shoulder function score were significantly improved compared to those before surgery(P＜0.05),and the function of the affected shoulder joint was basically restored to normal.Conclusion:Debridement and antibiotic-loaded calcium sulfate implantation for the treatment of clavicular osteomyelitis not only can effectively control infection,preserve the shape and function of the clavi-cle well,but also have a low recurrence rate of postoperative infection,simple surgical operation,and no serious complica-tions,which is worthy of clinical promotion.
NETL
NSTL
万方数据
维普
