Bone tissue engineering is an effective way to repair bone and cartilage damage.At present,many materials have been used in bone tissue engineering,and nano-drug loading materials are one of them.The particle diameter of nano-drug-loaded materials is much smaller than that of capillaries,which has the advantages of reducing drug toxic side effects,improving drug stability,sustained and controlled release of drugs,and targeted drug release.Many traditional Chinese medicine(TCM)molecules have been shown to play important roles in promoting bone and cartilage regeneration.In addi-tion to the advantages of traditional nanomaterials,molecular nanomaterials loaded with TCM also have special therapeutic abilities such as promoting the regeneration of osteoblasts and chondrocytes,maintaining the structure of bone cells,and inhibiting inflammatory factors,which can provide new ideas for bone tissue engineering to promote bone and cartilage re-pair.This paper summarizes the major active constituent of TCM molecular nanomaterials and the types of currently used in tissue engineering,will take TCM medicine molecular nanomaterials and the prospect in the application of bone tissue engineering.
关键词
载药纳米材料/淫羊藿苷/姜黄素/组织工程/骨与软骨修复/支架
Key words
nano-loaded drug/icariin/curcumin/tissue engineering/bone and cartilage regeneration/scaffold
维普
万方数据